Open source Bio instruments¶
Introduction¶
Our project is to basically create an Open source bio instrument, specifically a micro pump, and to validate the results we get from it. And for that we’ll be creating two pump and comparing between them. The pumps we’re aiming to design has to be an open source bio instrument that will be feasible for people with limited lab instruments to use.
Both of the pump will be a positive displacement pump and that’s because positive displacement pumps are much cheaper than others and it maintains constant flowrate and that’s exactly what’s needed in the medical applications
principles of creating bio instruments (micro fluid device)¶
• Controller software (Python) and a graphical user interface (GUI) to control the pumps. • Arduino firmware to send commands to the motors and receive commands from the GUI. • Bill of materials for sourcing and purchasing materials. • Detailed assembly instructions of hardware components. • Single click executable files for Mac, Windows, Linux, and Raspberry Pi systems.
Methods of calibrating positive displacement pumps :¶
1-By the volume efficiency.¶
The pump volumetric efficiency depends on : -The pressure drop - The viscosity of the fluid -The pump technology/ mechanism • Wet calibration using actual fluid flow. • Measurement check of physical dimensions and use of empirical gables relating flow rate to these dimensions. • Dry calibration using flow simulation by electronic or mechanical means.
Design Principles¶
We strove to produce a bioinstrument that could be readily implemented and modified by others: users and designers who could improve and expand on the system. We considered that bioinstrument users generally fall into two categories: i) those who want to adopt a design and use it in a straightforward manner, and ii) those who want to tweak, improve, and adapt designs to their needs, utilizing the instrument for new use cases. While cost is one motivation for developing and using open source instruments, low cost alone cannot drive the adoption of a project for these two groups. A successful open source instrument appeals to the needs of basic and advanced users by adhering to a set of clear design principles: functionality, robustness, safety, simplicity, modularity, benchmarking, and documentation. Adhering to these principles from the beginning of the design-build-test cycle will result in improved bioinstruments ready for further development and use by others.
steps of 3d printing¶
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